Biotechnology

Animal Cell Culture Technology

Bioprocess Development in animal cell culture and microbial culture with the goals to optimize production processes of bio-products using.

Upstream process: lab scale and large scale animal cell culture, microbial culture and IgY antibody production.

Downstream processes: purification of bio-products such as viruses, virus-like particles, recombinant proteins and antibodies from animal cell culture, microbial culture and egg yolk.

Head of Laboratory

Algal Biotechnology

  • Mass cultivation of Spirulina and microalgae.
  • Production of high-value chemicals from microalgae.
  • Molecular biology of microalgae.
  • More Information http://www.algaltech.kmutt.ac.th
Head of Laboratory

Sensors Technology

  • Electrochemical and optical labels for high sensitivity and simultaneous / multiplex assays for nucleic acid and protein detection.
  • Development of robust molecule specific biosensors for environmental applications.
  • Lab-on-a-chip for point-of-care clinical diagnostics.
Head of Laboratory

Fungal Biotechnology

  • Modeling of PKSMT production from Xylaria sp. BCC1067 in Aspergillus oryzae.
  • Pilot-scale production of essential fatty acids from Mucor spp. by submerged and solid-state fermentation.
  • Study of lipogenesis in oleaginous yeasts and fungi by comparative genomic analysis.
Head of Laboratory

Biodiversity

  • Biodiversity of endophytic fungi and bacteria of economically important crops and plants and plant-microbe interactions.
  • Screening for bioactive metabolites such as anti-cancer agents, antimicrobial agents and pigments from endophytic fungi and bacteria.
  • Polysaccharide from submerged culture of mushrooms: production, biological activity and characterization.
Head of Laboratory

Microbial Fermentation Technology

  • Large-scale production of protease and essential fatty acid from filamentous fungi using submerged fermentation.
  • Ethanol fermentation from Zymomonas mobilis and yeast.
  • Autolysis and its related lytic enzymes of Aspergillus oryzae during fermentation.
  • Poly-unsaturated fatty acid from filamentous fungi in submerged fermentation.
Head of Laboratory

Remediation

  • Development of adsorbents from agricultural wastes for treatment of wastewater containing organic substances and heavy metals/recovery of valuable metals.
  • Phytoremediation of waste-water/soil contaminated with heavy metals and organic substances by local Thai plants.
  • Removal of color from food industry waste by local materials.
Head of Laboratory

Excellent Center of Waste Utilization and Management (ECoWaste)

  • Microbiological and Biochemical Aspect: Basic knowledge of microbiological and biochemical mechanisms of anaerobic digestion (AD), modified high effective AD microbes, development of novel microbial techniques to quantify and qualify AD microbes using molecular approaches.
  • Reactor and Process Development:Anaerobic reactor design and development with high efficiency along with biogas purification.
  • Computational Aids and Process Optimization: Mathematical models to predict biochemical pathway and hydrodynamic mechanisms in AD to control its treatment efficiency, development on-line measurement for the control of the biogas reactor.
  • Environmental Research and Management: Water and energy audit for increasing efficiency and optimize the utilization of natural resources, water, and energy in the tapioca starch industry to a near-zero discharge starch factory, with the aim of determining the capacity and limitations of production.
Head of Laboratory

Solid State Fermentation and Bioprocess Engineering

  • Development of therapeutic protein production and purification processes using recombinant Pichia pastoris.
  • Production of biologically active compounds (enzymes, biocontrol agents, fatty acids) using various microorganisms by solid state fermentation of agricultural by-products in rotating drum bioreactors.
Head of Laboratory